Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation
Most prostate cancers Inlet Hose (PCas) are classified as acinar type (conventional) adenocarcinoma which are composed of tumor cells with luminal differentiation including the expression of androgen receptor (AR) and prostate-specific antigen (PSA).There are also scattered neuroendocrine (NE) cells in every case of adenocarcinoma.The NE cells are